The OEIS complex (omphalocele, exstrophy, imperforate anus, spinal defects).

نویسندگان

  • J C Carey
  • B Greenbaum
  • B D Hall
چکیده

The OEIS complex comprises a combination of defects including omphalocele, exstrophy of the cloaca, imperforate anus, and spinal defects. It may represent the most severe manifestation of a spectrum of birth defects, the exstrophy-epispadias sequence. The OEIS complex affects 1 in 200,000 to 400,000 pregnancies and is of unknown cause. The purpose of the current report is to document the occurrence of OEIS in sibs from separate pregnancies and suggest that some cases may have a genetic basis.

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منابع مشابه

Omphalocele, exstrophy of cloaca, imperforate anus and spinal defect (OEIS Complex): A case report

Omphalocele, exstrophy of cloaca, imperforate anus and spinal defect (OEIS Complex) is an extremely rare combination of serious defects, which was firstly described by Carey and colleagues. Surgical repair of cloacal exctrophy in patients with OEIS complex can be performed at one stage, but it can also be performed safely as staged to minimize the potential complications. In this case report, w...

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OEIS complex

OEIS is a malformative complex that associates an omphalocele, an exstrophy of the cloaca, an anal imperforation and spinal defects. Normal development of the cloaca gives origin to the lower abdominal wall with bladder, intestine and anus, genitals organ and part of the pelvis bones and lumbosacral spine. Incidence of OEIS is rare, thought to occur in 1 in 200,000 to 1 in 250,000 live births. ...

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Perinatal Autopsy Finding in OEIS Complex Associated with Other Congenital Anomalies

OEIS complex is one of the congenital anomalies not compatible with life. It comprises of omphalocele, exstrophy of the cloaca, imperforate anus and spinal defects with incidence of 1:100,000 live births. It can be associated with other anomalies of urinary tract, genital tract, skeletal defects variably. Diagnosis can be done prenatally by ultrasonography. We present a case of OEIS complex wit...

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Multimodality Renal Failure in a Patient with OEIS Complex

Omphalocele-exstrophy of the bladder-imperforate anus-spinal defect (OEIS) complex is a rare constellation of clinical abnormalities with wide phenotypic presentation. We describe a case of a preterm neonate with OEIS complex with acute renal failure, and the challenges in diagnosis and management of this patient as renal failure can be a multifactorial process when encountered with this rare c...

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OEIS complex associated with chromosome 1p36 deletion: a case report and review.

OEIS complex (Omphalocele, Exstrophy of the cloaca, Imperforate anus, and Spine abnormalities) is a rare defect with estimated incidence of 1 in 200,000 live births. Most cases are sporadic, with no obvious cause. However, it has been rarely reported in patients with family members having similar malformations or with chromosomal anomalies. In addition, OEIS complex has been observed in associa...

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عنوان ژورنال:
  • Birth defects original article series

دوره 14 6B  شماره 

صفحات  -

تاریخ انتشار 1978